GOUT – DESCRIPTION
Some proteins are broken down, in the body, and uric acid is formed. This substance is normally present in the blood and is excreted by the kidney. In gout, there is either an over-production or an under-excretion of uric acid. In some, there is a combination of both.
Uric acid builds up in the blood and is deposited as urate crystals in joints and the tissues around them. Urates may also be deposited as gouty tophi in other tissues, such as the ear or around the elbow.
The first indication is usually an acute arthritis. In most cases this involves the big toe, but any other joint may be involved. Occasionally, several joints are involved at the same time.
The pain comes on suddenly and is severe and throbbing. The joint is usually swollen and the skin overlying it is hot, reddened and shiny. The whole area is tender, and even light pressure on the skin is painful. Fever may accompany the attack. Unless treated, each such attack may last from five to seven days.
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